They are the building blocks
of who you are. They make up
your personality and affect
your health. But what do
your genes reveal? From
baldness to blindness,
hundreds of Internet tests
promise to give a digital
glimpse into your future.
"As you get older and when
you have children, you
become more and more
interested about what's
going to happen to you and
what you are going to pass
on to them," Harriett Levin
Balkind told Ivanhoe.
Levin Balkind keeps fit
inside and out, but she
worries about what she can't
control -- Parkinson's,
hereditary heart disease and
Alzheimer's.
"My husband's father died
of Alzheimer's and on my
side of the family, my
father's sisters both had
Alzheimer's," she said.
She and her husband
turned to a private company
to test their DNA … not only
for themselves, but to help
predict future health issues
of their only son.
"It's such a fascinating
way to learn about yourself
and we thought why not take
this out to individuals,
give them an opportunity to
learn about their own
genetics?" Linda Avey,
co-founder of 23andMe in
Mountain view, Calif., said.
Avey
and Anne Wojcicki are the
creators behind 23andMe -- a
simple $399 test that was
named Time magazine's
Invention of the Year.
"It's all in the saliva
and it's just a matter of
measuring those points in
the genome," Avey explained.
The home test takes some
spit that's sent off to a
lab. Results of more than
100 traits are posted on a
password protected website.
"The first thing it told
me, which completely blew me
away, was you're an
Ashkenazi Jew, and that just
was amazing to me" Levin
Balkind recalled.
Your DNA can be traced
back to its roots, showing
the journey of your
ancestors, tracking each
generation. The past is very
definitive. The future is
not so black and white.
"We're looking at the
genetics of more common
diseases and they're not so
deterministic," Avey said.
"You could have an increased
risk for something like
heart disease or rheumatoid
arthritis. That doesn't mean
you're going to get the
disease."
Critics warn tests like
these can be deceiving.
"If you do a DNA test on
someone to predict their
risk of heart disease,
you're really only looking
at a part of the picture,"
Marta Gwinn, M.D., M.P.H., a
medical epidemiologist in
the National Office of
Public Health Genomics at
the Centers for Disease
Control and Prevention in
Atlanta, said. "You're
really only looking with
what they came with -- the
hand they were dealt -- when
we know that so much of your
future health depends on how
that hand is played."
"People
might be a little startled
at first with the
information, but I'd say all
in all, for those people who
are fearful of getting this
information, they're just
not signing up to begin with
and the people who are
signing up are those who
say, 'I think information is
power,'" Avey said.
"Knowing yourself and
knowing how you're going to
react to having information
is really important and
critical for any genetic
test," Susannah Baruch,
J.D., the law and policy
director at Johns Hopkins
University's Genetics and
Public Policy Center in
Washington, D.C., said.
Kaye Neufeld knows she's
strong. She's a cancer
survivor. Her reason for
taking the test?
"Six years ago I was
diagnosed with breast cancer
and it came to me as a shock
because I had done
everything right," she
explained. "I've been on a
mission to find out maybe
why this happened."
For Neufeld, 23andMe did
not give her the answer she
was looking for.
"They did test for three
breast cancer genes and I
didn't carry any of the
risks for that, so I still
think there's something else
going on with genetics, and
I'm still looking for that
answer," she said.
But the test did reveal
Neufeld has a 55 percent
risk for blood clots -- the
same condition that killed
reporter David Bloom in
Iraq.
"Now that I know, I can
be proactive and be sure
that I get plenty of
exercise and move my legs
and help to prevent that
from happening to me,"
Neufeld said.
Levin Balkind's husband
found out what was causing
his lifelong stomach
problems.
"The test results show
that I am lactose
intolerant," Aubrey Balkind
explained. "I went to a
doctor and they confirmed,
yes, I have lactose
intolerance."
As for Levin Balkind,
Alzheimer's is not part of
the 23andMe DNA test yet,
but she did learn that she
was low risk for Parkinson's
and a high risk for diabetes
and high blood pressure.
"It makes you realize you
have control -- that you
have more control than you
thought," she said.
Gene experts warn this is
a new field. They're
learning more about the
human genome every day.
Results will change and
people need to be aware that
test results are not written
in stone.
"This
isn't definitive yet," Avey
explained. "We're really on
the cutting edge of this, so
it has to be taken in the
proper light -- that it can
change."
"I wouldn't want to be
seen as arguing against the
research or against the
development of useful
tests," Dr. Gwinn said. "I
just want people to think
before they spit and use
their money wisely."
Once you take the test,
23andMe updates any new DNA
information as it's
revealed. They hope to test
for Alzheimer's in the next
few years. The company is
also heavily involved in
research. They ask each
person who signs up to allow
their DNA to be part of
clinical trials and research
studies.