Researchers in Europe found women who had
higher levels of perfluorooctanoate (PFOA) and perfluorooctane
sulfonate (PFOS) in their blood took longer to get pregnant than
women with lower levels. Perfluorinated chemicals (PFCs) like
PFOA and PFOS are widely used in food packaging, pesticides,
clothing, upholstery, carpets and personal care products. They
remain in the environment and the body for decades.
To get their data, samples from 1,240 women
were analyzed. PFOS blood levels ranged from 6.4 nanograms per
milliliter (ng/ml) to 106.7 ng/ml, and PFOA levels from less
than 1 ng/ml to 41.5 ng/ml. PFOS/PFOA blood levels were divided
into four quartiles. Compared to women with the lowest levels of
chemical in their blood, the likelihood of infertility increased
by 70 to 134 percent for those in the higher three quartiles of
PFOS and 60 to 154 percent for those in the higher three
quartiles of PFOAs.
"As far as we know, this is the first study
to assess the associations between PFOA and PFOS levels in
plasma with time to pregnancy in humans," Jorn Olsen, principle
investigator and a professor and chair of the department of
epidemiology at the University of California, Los Angeles, was
quoted as saying. "We are waiting for further studies to
replicate our findings in order to discover whether PFCs should
be added to the list of risk factors for infertility."
SOURCE: Human Reproduction,
published online January 29, 2009